NAD+ (Nicotinamide Adenine Dinucleotide) is a crucial coenzyme found in every cell of your body that powers hundreds of metabolic processes. It serves as a key player in cellular energy production, DNA repair, and cellular communication. NAD+ works by transferring electrons during cellular metabolism, enabling your cells to convert nutrients into energy and supporting essential functions that keep your body running optimally.

NAD+ levels naturally decline from birth, accelerating around age 30, and dropping by up to 65% by age 70. Environmental and lifestyle stressors also diminish NAD+ levels, as do immune and health challenges. Taking a clinically proven supplement like Tru Niagen helps maintain your NAD+ baseline levels with daily use—to keep your body running smoothly as you age.

What is the difference between Tru Niagen and other NAD brands on the market?

Tru Niagen is a superior choice compared to other NAD supplements because it contains Niagen®, our patented nicotinamide riboside (NR), a more bioavailable precursor to NAD+. Niagen® NR is backed by 45+ human clinical studies, and crosses cell membranes easily and is more efficiently converted into NAD+ inside cells, effectively boosting NAD+ levels. 

This enhances energy metabolism, supports cellular repair, and promotes healthy aging, making Tru Niagen a more reliable, high-quality, pure, and potent option for raising NAD+ compared to other supplements. Tru Niagen® is clinically shown to increase NAD+ levels by over 50% with 300mg daily and by up to 150% with 1000mg daily and is backed by third-party quality-testing from NSF Certified for Sport and Alkemist Labs.

Cellular NAD+ support begins immediately upon supplementation. However, the cellular health benefits of increased NAD+ levels begin immediately, even before you feel noticeable changes.  

Tru Niagen begins elevating NAD+ levels within hours of taking your first dose, with significant increases observed within 2 weeks of daily supplementation. For optimal results, we recommend taking Tru Niagen consistently as part of your daily routine. 

Tru Niagen has been rigorously tested for safety and is well-tolerated. Our proprietary key ingredient Niagen® has successfully completed multiple FDA safety reviews and is manufactured in cGMP-certified facilities in the USA.  

Niagen is supported by 45+ clinical studies demonstrating its safety and efficacy. These human studies form the foundation of our scientific evidence. Over 75% of published peer-reviewed clinical studies on NR use Niagen® NR. Niagen is also backed by independent research, with over 90% of Niagen studies being investigator-driven and third-party funded. 

In clinical studies, participants reported minimal to no side effects when taking the recommended dosage up to 2,000mg per day. Some individuals may experience mild and temporary effects that typically resolve quickly. As with any supplement, we recommend consulting with your healthcare provider before starting Tru Niagen, especially if you have existing health conditions or take medications

Subscribers enjoy exclusive savings of 20% off every order, free shipping, and automatic delivery of Tru Niagen every month on your schedule. You can pause, skip, or adjust your subscription any time, risk-free. It’s the easiest way to ensure consistent NAD+ support for your daily health, while saving on every bottle.

Tru Niagen 300mg features the key active ingredient, Niagen® and is our foundational serving size and clinically shown to increase NAD+ levels.  Other serving size option such as 150mg or 1000mg are other options for people who may want smaller capsule size in the 150mg, or choose a higher serving found in the Tru Niagen Pro 1000mg based on your lifestyle or age.  

Everyone’s health needs vary and it’s recommended to work closely with your healthcare provider to determine the best serving size for your health goals. The ideal serving for you depends on your lifestyle, your age, and other factors. Try taking our Product Quiz to see what serving might be right for you. 

The Conze et al., 2019 clinical study supplemented participants with 100mg, 300mg, or 1000mg of Niagen daily. NAD+ increased over 50% in 2 weeks and was maintained throughout the 8-week study with 300mg, and up to 150% with 1000mg.